Probing the

Origin of Cell Communication

in Animals

image credit: Animation Lab, University of Utah.

Kinase
Signaling

We aim to uncover the physiological role of phosphotyrosine signaling during the origin of multicellularity in animals. We use a combination of targeted genetics, pharmacology, and biochemistry to uncover kinase signaling.

Team Members: Maria, Viky

Selected Preprint

Rutaganira FUN, Coyle MC, Scopton AP, Dar AC, King N. A stress-responsive p38 signaling axis in choanoflagellates. bioRxiv. 2022 (Link)

 

Stay tuned for upcoming publications!

Chemical
Ecology

We study how choanoflagellates interact with their prey, bacteria, which also induce choanoflagellate development.

Team members: Yvette, Bri

 

Stay tuned for upcoming publications!

Multicellular
Origins

We investigate how the unicellular relatives of animals use cell surface receptors to detect extracellular signals and how extracellular signaling impacts choanoflagellate cell biology.

Team Members: Jia, Hannah

 

Stay tuned for upcoming publications!

© Florentine Rutaganira

Shopping Basket